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Part 1 enrollment complete Biopsy-proven metastatic pancreatic adenocarcinoma with documented rfedericia disease progression on or after one or more systemic therapies. Chemotherapy given as part of prior chemoradiation in the setting of non-metastatic pancreatic cancer does not count as a line of therapy. Chemotherapy given for at least 4 months as adjuvant after complete response is considered as a first line therapy. Part 2 actively enrolling Biopsy-proven metastatic pancreatic adenocarcinoma on or escort space coast two prior lines of systemic therapy. Chemotherapy given as part sex text fredericia prior chemo- radiation in the setting of non-metastatic pancreatic cancer does not count as a line of therapy unless metastases develop within 6 months of completing the chemosensitization. Chemotherapy given for at least 4 months as adjuvant after a CR to any therapy e.

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